Cell longevity: the basis of younger appearance.
After the age of 60 wrinkles are joined by other signs of passing time. Decreasing skin tone results in the change of the face contour which is no longer firm and clearly defined. The surface of the skin has a dull, coarse and uneven texture, and tends to be reddened or hyperpigmented.
These skin dysfunctions results from the decreased efficiency of cell physiology and lead to the formation of tissues built of “ageing” cells. The cells become senescent after fewer replications cycles as a result of cumulative DNA damage which can no longer be effectively repaired.
In order to extend cell life-span and ensure enhanced, healthy cell function, Dr Irena Eris Centre for Science and Research developed an innovative active ingredient Telomeric™. It maintains telomeres ( the regions of DNA at the ends of chromosomes) in a good condition, which results in a faster rate of skin structure regeneration, and significantly delays fibroblast ageing.
The new Telomeric™ range recommended for women aged 60 plus ensures an evenly coloured skin free from deep wrinkles, erythema, dilated pores or hyperpigmentation, and restores firm and clearly defined facial features.
Telomeric™ skin care line includes:
Dermal Filling repair cream – night care
Concentrated lifting cream SPF 15 – day care
Telomeric™ products ensure the following results:
1. Improved skin structure:
– increased skin tonus
– smoothed out lines and deep wrinkles
– reduced visibility of dilated skin pores
2. Restored proper function of the skin:
– restored proper skin hydration levels
– restored protective function of the skin
– reduced hyperpigmented lesions – age spots
A telomere is a region of repetitive DNA at the end of a chromosome, which protects the end of the chromosome from deterioration during replication. Its name is derived from the Greek nouns telos (τέλος) “end” and merοs (μέρος, root: μερ-) “part”. Telomeres act like bookends, keeping chromosomes from fusing into rings or binding haphazardly with other DNA.
The Biology of Cell Division
Each time a cell divides, the information in the DNA is copied onto two “daughter” cells. However not all of the DNA information is copied. The enzyme molecules responsible for replication are unable to completely reproduce the tips of a chromosome. For divison and therefore replication to occur, a strand of DNA has to be “snipped” in the telomere region.
Telomeres and Aging
Studies have shown that older people generally have shorter telomeres. Eventually, the cells with shorter telomeres can no longer replicate properly and, over time and lots of cells, this process displays itself in what we call “aging.”
Researchers now believe that the shortening of telomeres plays a crucial role in the aging process. Over time, telomeres can become too short, resulting in damage to essential parts of the DNA during the replication process. Eventually, they become too short to allow for cell division and the cell eventually dies. In humans, a cell replicates about 50 times before the telomeres become too short. This limit is called the Hayflick limit (after the scientist who discovered it).
Telomeres and Skin Health
As we age, our skin undergoes visible changes, which include those attributable to the passage of time alone (intrinsic aging) and changes due to imposed, external factors (extrinsic aging), such as chronic sun exposure or reactive oxygen species (ROS).
As the most the most superficial part of the body, the signs of aging are most visible in the skin and numerous studies have confirmed a link between telomere shortening and signs of aging in the skin. Like any other part of the body, the DNA sequencing of the skin is subject to telomere shortening. However, researchers now believe that telomeres in skin cells may be particularly susceptible to accelerated shortening, due to both the rate of proliferation and DNA-damaging agents such as ROS, also known as free radicals. ROS can result from a variety of causes, including exposure to environmental toxins and excessive amounts of sunlight. The result of this accelerated shortening is the tissue degeneration we normally associated with the signs of aging.
Although aging skin is not a health threat per se, promoting the health of your skin should be part of your daily routine.
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